Chapter 8 : Pertussis
نویسنده
چکیده
Pertussis, or whooping cough, is caused by the bacterium Bordetella pertussis. It is characterized by paroxysmal coughing followed by a characteristic inspiratory whoop. Secondary bacterial pneumonia is the cause of most pertussis-related deaths. Other complications, though infrequent, can include neurological complications such as seizures and encephalopathy, otitis media, and conditions resulting from the pressure effects of severe paroxysmal coughing including pneumothorax, epistaxis, subdural hematomas, hernias, and rectal prolapse. Disease rates and risk of serious complications, including death, are highest among young children, particularly those <1 year of age; disease in adolescents and adults tends to be milder.
منابع مشابه
Seroprevalence of IgG Antibodies against Bordetella pertussis in Different Age Groups in Tehran, Iran
Background and Aims: Pertussis is a highly contagious, vaccine-preventable disease. Determination of the seroepidemiology of pertussis makes possible the evaluation of pertussis immunity in a population. In this study, we determined the seroprevalence of Bordetella pertussis IgG antibodies in different age groups in Tehran, Iran. Materials and Methods: Overa...
متن کاملThe Impact of Early Postpartum Maternal Pertussis Vaccination on the Protection of Infants: A Randomized Clinical Trial
Background: Despite primary vaccination, infants under six months run a risk of infection with pertussis. Objective: To determine the impact of early postpartum maternal pertussis vaccination on protecting infants from the disease. Methods: All mothers (n=405) who gave birth to healthy term infants were educated on the cocoon strategy. The moth...
متن کاملSerologic Evidence of Pertussis Infection in Vaccinated Iranian Children
Background: It seems that the incidence of pertussis-like illnesses is considerably increasing despite the wide coverage of immunization with the whole cell pertussis vaccine. We aimed to investigate the occurrence of pertussis in vaccinated children by measuring anti-pertussis antibodies. Methods: In this cross-sectional study, blood samples were taken from vaccinated children aged 2, ...
متن کاملRegulation of pertussis toxin and lipopolysaccharide levels of Bordetella pertussis 134 in response to modulators
Whooping cough (pertussis) is a highly contagious disease of the human respiratory tract, which is caused by Bordetella pertussis. Reemerge of pertussis in some highly immunized populations and divergency in gene order among several B. pertussis strains promoted this research to study the change of pertussis toxin (PT) and lipopolysacharide levels in response to the different environments. Th...
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تاریخ انتشار 2000